Summary and Bibliography of Chapter 6

1. There is a vast potential market for biosensors which is only beginning to be expoited.

2. Biosensors generally are easy to operate, analyse over a wide range of useful analyte concentrations and give reproducible results.

3. The diffusional limitation of substrate(s) may be an asset to be encouraged in biosensor design due to the consequent reduction in the effects of analyte pH, temperature and inhibitors on biosensor response.

References and Bibliography

1. Albery, J., Haggett, B. & Snook, D. (1986). You know it makes sensors. New Scientist 13th Feb., 38-41.

2. Bergmeyer, H.U. ed. (1974). Methods of Enzymatic Analysis 3rd edn, New York: Verlag Chemie, Academic Press.

3. Guilbault, G.G. & de Olivera Neto, G. (1985). Immobilised enzyme electrodes. In USES45,1 Immobilised cells and enzymes A practical approach ed. J.Woodward, pp 55-74. Oxford: IRL Press Ltd.

4. Hall, E.A.H. (1986). The developing biosensor arena. Enzyme and Microbial Technology  8, 651-657.

5. Joachim, C. (1986). Biochips: dreams...and realities. International Industrial Biotechnology 79:7:12/1, 211-219.

6. Kernevez, J.P., Konate, L. & Romette, J.L. (1983). Determination of substrate concentration by a computerized enzyme electrode. Biotechnology and Bioengineering 25, 845-855.

7. Kricka, L.J. & Thorpe, G.H.G. (1986). Immobilised enzymes in analysis. Trends in Biotechnology4, 253-258.

8. Lowe, C.R. (1984). Biosensors. Trends in Biotechnology 2, 59-64.

9. North, J.R. (1985). Immunosensors: antibody-based biosensors. Trends in Biotechnology 3, 180-186.

10. Russell, L.J. & Rawson, K.M. (1986). The commercialisation of sensor technology in clinical chemistry: An outline of the potential difficulties. Biosensors 2, 301-318.

11. Scheller, F.W., Schubert, F., Renneberg, R. & Mes82,5≈ ller, H-G. (1985). Biosensors: Trends and commercialization. Biosensors 1, 135-160.

12. Turner, A.P.F. (1987). Biosensors: Principles and potential. In Chemical aspects of food enzymes, ed. A.T.Andrews, pp 259-270, London: Royal Society of Chemistry.

13. Turner, A.P.F., Karube, I. & Wilson, G.S. eds. (1987). Biosensors: Fundamentals and applications, Oxford, U.K: Oxford University Press.

14. Vadgama, P. (1986). Urea pH electrodes: Characterisation and optimisation for plasma measurements. Analyst111, 875-878.bp