Enzyme Technology
Immobilised-enzyme processes
Immobilise -enzyme systems are used where
they offer cost advantages to users on the basis of total manufacturing costs.
The plant size needed for continuous processes is two orders of magnitude
smaller than that required for batch processes using free enzymes. The capital
costs are, therefore, considerably smaller and the plant may be prefabricated
cheaply off-site Immobilised enzymes offer greatly increased productivity on an
enzyme weight basis and also often provide process advantages (see Chapter
3)
Currently used immobilised-enzyme processes are given in Table
5.1.
Table 5.1 Some of the more important
industrial uses of immobilised enzymes
|
Enzyme
|
EC number
|
Product
|
|
Aminoacylase
|
3.5.1.14
|
L-Amino acids
|
|
Aspartate ammonia-lyase
|
4.3.1.1
|
L-Aspartic
acid
|
|
Aspartate 4-decarboxylase
|
4.1.1.12
|
L-Alanine
|
|
Cyanidase
|
3.5.5.x
|
Formic
acid (from waste cyanide)
|
|
Glucoamylase
|
3.2.1.3
|
D-Glucose
|
|
Glucose isomerase
|
5.3.1.5
|
High -fructose corn syrup
|
|
Histidine ammonia-lyase
|
4.3.1.3
|
Urocanic acid
|
|
Hydantoinase a
|
3.5.2.2
|
D- and L-amino acids
|
|
Invertase
|
3.2.1.26
|
Invert sugar
|
|
Lactase
|
3.2.1.23
|
Lactose-free milk and whey
|
|
Lipase
|
3.1.1.3
|
Cocoa butter substitutes
|
|
Nitrile hydratase
|
4.2.I.x
|
Acrylamide
|
|
Penicillin amidases
|
3.5.1.11
|
Penicillins
|
|
Raffinase
|
3.2.1.22
|
Raffinose-free
solutions
|
|
Thermolysin
|
3.2.24.4
|
Aspartame
|
a Dihydropyrimidinase.
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This page was established in 2004 and last updated by Martin
Chaplin
on
6 August, 2014
|